Measles Outbreak Investigation in Village Bara, Khyber Agency, Pakistan-February 2017: Case Control Study

Measles Outbreak Investigation in Village Bara, Khyber Agency, Pakistan-February 2017: Case Control Study

Measles Outbreak Investigation in Village Bara, Khyber Agency, Pakistan-February 2017: Case Control Study

Authors of this article:

Muhammad Ismail ;   A Khan

Abstract

Corresponding Author:

Muhammad Ismail


Background: Measles is highly contagious and remains a leading cause of childhood mortality. Outbreaks of Measles were reported from various parts of Pakistan, particularly tribal areas. In February 2017 Measles outbreak was reported from Bara, Khyber Agency.

Objective: To confirm the outbreak, assess its magnitude, identify risk factors and to implement prevention and control activities to stop spread of the outbreak.

Methods: A case was defined as Rash with fever and cough, coryza or conjunctivitis in a child younger than 14 years of age, resident of Bara, during 3rd February to 15th March, 2017. Active search of cases done. Data was collected using a pretested structured questionnaire and analyzed using Epi Info version 7.1. Descriptive analysis was done followed by age & sex matched case control study. Case fatality rate, attack rate, vaccine efficacy, and secondary infectivity rates were calculated.

Results: Total 42 cases were identified. The Epi curve ranges from 3rd February to 15th March with a bi-modal peak on 23rd Feb and 5th March. Mean age of the cases was 37 months (range 1-120 months). Males were 52.38% (n=22). Socioeconomic status of parents was poor (28.57%laborers, 38.10% earn below 10000 PKR/month, 59%fathers were literate while all mothers were illiterate). Case Fatality rate was 7.14% (n=3). Vaccination showed protective effect [OR 0.12 (95% CI: 0.03-0.40; P<.05)]. Vaccination coverage survey showed 46.3% coverage for Measles-1. Secondary infectivity was high in houses where children were more than 7 in number [OR 8.67 (95% CI: 1.76-42.6, P<.05). Distance from health facility (>3kms) showed higher odds of getting the illness [OR 2.89 (95%CI: 1.22-6.84); P<.05].

Conclusions: This study in a post-conflict repatriated population showed relationship of low socioeconomic status, low vaccination coverage, distance from health facility and overcrowding with the disease. Awareness sessions and mop-up vaccination in the area contributed in controlling the outbreak.

iproc 2018;4(1):e10593

doi:10.2196/10593


Edited by Y Khader; This is a non–peer-reviewed article. submitted 29.03.18; accepted 29.03.18; published 29.03.18

Copyright

©Muhammad Ismail, A Khan. Originally published in Iproceedings (http://www.iproc.org), 29.03.2018.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in Iproceedings, is properly cited. The complete bibliographic information, a link to the original publication on http://www.iproc.org/, as well as this copyright and license information must be included.