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(F) Lower socially active dwell time in AD versus HCs, and an interaction between socially active dwell time and AD when predicting social functioning, were observed. AD: Alzheimer disease; HC: healthy control; SCC: subjective cognitive complaints; SZ: schizophrenia; S1: state 1; S2: state 2; zt: hidden state at time point, t. Where we use “1-hot” encoding for the latent variable, such that ztn=1 if the latent variable at time t belongs to the class n, and 0 otherwise.

Imogen E Leaning, Andrea Costanzo, Raj Jagesar, Lianne M Reus, Pieter Jelle Visser, Martien J H Kas, Christian F Beckmann, Henricus G Ruhé, Andre F Marquand

J Med Internet Res 2025;27:e64007

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Correction: Assessment and Intervention for Diabetes Distress in Primary Care Using Clinical and Technological Interventions: Protocol for a Single-Arm Pilot Trial

Marisa Kostiuk, Susan L Moore, E Seth Kramer, Joshua Felton Gilens, Ashwin Sarwal, David Saxon, John F Thomas, Tamara K Oser

JMIR Res Protoc 2025;14:e75984

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Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

Beth E Meyerson, Alissa Davis, Richard A Crosby, Linnea B Linde-Krieger, Benjamin R Brady, Gregory A Carter, Arlene N Mahoney, David Frank, Janet Rothers, Zhanette Coffee, Elana Deuble, Jonathon Ebert, Mary F Jablonsky, Marlena Juarez, Barbara Lee, Heather M Lorenz, Michael D Pava, Kristen Tinsely, Sana Yousaf

JMIR Res Protoc 2025;14:e69829

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Detecting Sleep/Wake Rhythm Disruption Related to Cognition in Older Adults With and Without Mild Cognitive Impairment Using the myRhythmWatch Platform: Feasibility and Correlation Study

From the extended-cosine models, we extracted measures of 24-hour robustness (pseudo-F statistic, indicating how well the observed data fits the 24-hour curve); activity onset time (up-mesor, the time which the modeled activity level passes the middle modeled rhythm height prior to the peak); and activity offset time (down-mesor or the time which the modeled activity level passes the middle modeled rhythm height prior to the nadir).

Caleb D Jones, Rachel Wasilko, Gehui Zhang, Katie L Stone, Swathi Gujral, Juleen Rodakowski, Stephen F Smagula